The performance potential of bacteriochlorin compounds have long been coveted by industry, however, known examples of these molecules were synthetically challenging, their spectra not easily tunable, and they could be thermally unstable. The bacteriochlorins synthesized in Dr. Lindsey’s laboratory overcome these limitations. Their structure allows for common starting materials and has been modified to increase thermal and photostability. Synthetic pathways have been optimized to provide high yields and easy workups. These dyes are new-to-the-world in the sense that no one has been able to successfully develop and synthesize bacteriochlorins with these unique features until now.
These novel near infrared dyes offer significant advantages:
• Ultra Narrow emission bands 18-25 nanometers full width at half maximum
…- Generate cleaner data
…- Enable researchers and clinicians to analyze more colors in each sample
• Wavelength tunable
…- Tailor to fit with existing diagnostic instruments
• Family of dyes will support excitation by many lasers
Chlorins, Porphyrins and Bacteriochlorins are often referred to as the “pigments of life.” They are crucial to the energy-making mechanism of photosynthetic bacteria which many will argue drove the origin of life. Drs. Lindsey, Holten and Bocian have extensively researched and studied these compounds and developed versatile synthetic pathways and extensive tacit understanding for wavelength tuning.