Tuning Dye’s Wavelengths
Fluorescent dyes used in photonics-based instrumentation are not valuable unless they perform well with the lasers and detectors on existing instruments.
Tuning dyes to meet hardware specifications is a very difficult set of skills to develop. First, many structures of dyes are simply not amenable to wavelength tuning. Second, some structures are amenable to tuning but most dye chemistry labs do not have the knowledge base needed to synthesize, characterize, test, and archive the photophysical performance of various structures.
Consequently, these labs are left with a very ad-hoc means of developing dyes which leads to serendipitous methods of invention and development of useful structures.
NIRvana Sciences co-founders intimately understand how dye synthesis, characterization, testing, and archiving relationships between structures leads to a reliable model to tuning the wavelengths of its dyes. It is very important to note that our method of tuning does not require redesign or reengineering of the structure of the Bacteriochlorin molecule. Very small changes to chemistry effectively retunes the absorption and emission spectra.
The picture above illustrates how Bacteriochlorins can be tuned.
It is very important to note that Bacteriochlorins absorb light in the UV, Visible, and Near Infrared Spectrums (solid lines) but ONLY emit in the Near Infrared spectrum (dotted lines).
This family of Bacteriochlorins can be tuned to emit from 700 – 900 nanometers to support a wide variety of diagnostic and imaging applications.